Outbreak of COVID-2019 :
On December 2019, in Wuhan, Hubei province of China, appeared some pneumonia like illness in a cluster of people. Most of the patients had visited to seafood marked in following days. Until January 15,2020 there were 15 confirmed cases of the novel COVID-2019 with one reported death
According to World Health Organization (WHO)’s situation report 57 which was published on March 17, 2020 globally risk level of COVID-2019 is very high.Until March 17, 2020 there were confirmed 179111 cases of corona virus along with 7426 deaths due to severe acute distress respiratory syndrome. On March 11,2020 World Health Organization WHO recognized ongoing corona virus disease 2019 as a pandemic and a public Health emergency of International concern. China was the main epicentre of corona virus outbreak, on March 13, WHO announced Europe as new epicentre of corona virus disease.
SARS corona virus 2 :
It has been found in studies that virus originated from bats, from bats it got transferred to some other mammal thus modified itself and transferred to humans, most probably in a seafood market.The novel corona virus is isolated from Human airways epithelial cells. It is an enveloped, non segmented, positive se se – RNA, beta corona virus. This infectious virus specifically belongs for subgenus sarbeco virus. So novel corona virus is more specifically a sarbeco virus, well its other family members can also infect humans.
Corona viruses contain RNA as their genetic material. They are six family members, and all six can infect humans. Two of them are:
- SARS-COV (severe acute respiratory syndrome coronavirus)
- MERS-COV(Middle East respiratory syndrome coronavirus)
During study of nCOV it was found that the virus is very much similar to SARS corona virus, belonging to sub genus serbeco virus. Scientists have named this virus as SARS-COV 2 virus. Host cells for COVID-2019 are Humans epithelial cells of respiratory system. During study it was found out that infection appeared in cells after 96 hours, after exposure to virus. Infected cells have also shown loss of ciliary beating.
COVID-2019 symptoms :
COVID-2019 causes symptoms like fever, dry cough, fatigue, shortness of breath, muscles or joint pain, sore throat, sputum production, head ache, chills, nausea or vomiting, diarrhoea, nasal congestion, haemoptysis, conjunctival congestion.Most common symptoms include fever, dry cough, sputum production however less commonly patients with COVID-2019 can also develop flu-like symptoms , runny nose, sneezing and it may remain asymptomatic.Diarrhoea, vomiting and nausea has been observed in minority of cases. In January 2020,these clinical finding were made out by enquiring addmitted patients and their records:
- Mostly affected patients were men
- Patients with hypertention, diabetes, and cardiovascular diseases
- 66% patients had been exposed to seafood market.
- SARS-COV 2 transmits through respiratory droplets of cougt and sneezes.
Treatment and medication:
Being announced as a pandemic follow these measures to avoid disease outbreak:
- Stay home
- Avoid travel and public activities
- Use sanitizers or wash hands for at least 20 seconds
- Avoid touching your face, nose or eyes
- Cover your mouth while sneezing and coughing
- If you don’t have any tissue while sneezing and coughing cough inside of your elbow
- Wash hands after sneezing and coughing
- Use mask only if you have cough and flu
- Use sanitizers with high alcohol content if soap and water is not readily available
- WHO recommended to produce sanitizers locally by using alcohol, hydrogen peroxide and glycerol, if not available at shops.
- Avoid close contact with unwell people.
Ibuprofen, which is an anti-inflammatory drug is commonly used for fever, should be avoided in case of COVID-2019 because it increases ACE 2 enzyme at cellular level which helps virus to spread. It can worsen the conditions. Use paracetamol instead.There is still no drug for treatment pf COVID-2019.WHO has proposed following measures for treatment.
Vaccine for Corona Virus :
As discussed earlier SARS corona virus 2 attacks the cells with ACE 2 enzyme so probably ACE 2 blockers can help to control the novel COVID-2019.Many scientists from all over the world are making experiments to make out a vaccine. An article from Wikipedia says that it may take until 2021 to develop a vaccine.
Is COVID-2019 a biologically modified weapon?
After outbreak of the novel corona virus there is a controversy that it is a biologically modified virus that was introduced in population by a proper plan but now new studies regarding COVID-2019 are going against this rumor. Fact to justify that it is not bio engineered, is that virus is being spread globally and it is not specifically targeting some specific community. COVID-2019 disease is a pandemic we should not convert it into an infodemic. Avoid rumors and must follow WHO precautions to help in controlling this pandemic until vaccine is developed.
“Diseases can make anyone sick regardless of their race”
Many vlogs and websites called it as a crafted virus, and according to them it is derived from HIV. Some of scientists made tweets says that might be the virus was stolen from Canadian lab and bio engineered by Chinese government to use it as a Weapon. However virology experts say that no such evidence exists that new corona virus is “man-made”. Scientists strongly condemn such conspiracies and misinformation about corona virus. Experts say that all evidences support the fact that virus is of natural origin, its peptide are more similar to pep tides contained in bats than that of HIV.
Global competition for developing COVID-2019 vaccine :
Many governments are making their best efforts to develop vaccine for COVID-2019 disease as the country who will develop vaccine will earn great values in future. Us and China are making their utmost efforts as relation between both countries are not on good grounds. Many other governments are in the race because these are governments who decide where vaccine will be exported and where not, after it is developed. China shared the genomic sequence to researchers of world, as soon as they got for development of vaccine. On the other hand, American president Donald Trump wants American and German pharmaceutical companies to develop vaccine as soon as possible in American as He can’t let any other government to win the race.
Israeli scientists are also claiming that they will announce first COVID-2019 disease vaccine in few coming weeks. Well rest of whole world is also ready to buy vaccine from Israel as soon as it will be developed. Well Australia is testing two drugs, one used for HIV and another for malaria on patients with COVID-2019 disease with some positive results. Professor Peterson from University of Queensland Centre for Clinical Research, told that patient when treated with drug used for HIV showed disappearance of virus COVID-2019, which is a quite good result.
White house offers German company to make vaccine in US:
German company CureVac is receiving offers form White House for making vaccine in US. While some sites are calling it rumors. These news are also on some websites that European commission has offered 80 millions euros to CureVac company for working on the vaccine. Many executives of pharmaceutical companies are more concerned about what after development of vaccine, vaccine is restrained to a population? Or if it is not exported to developing countries?
Many leading governments are making their utmost efforts to develop vaccination for COVID-2019, we hope that after development of vaccine it will be widely distributed to affected areas of population as soon as possible without any discrimination. Many experts are suspicious that vaccine developing country may stop its export to first saturate its own population. Vaccine developing country may charge bank-breaking charges to rest of countries for purchasing vaccination. But still there is a hope that vaccine developers will export it free to all other countries, especially to developing and under-developed countries for sake of humanity. We hope is case of vaccination humanity will cross the finish line earlier than any selfish decision.